Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 10/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | PKM | P14618 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NSUN3 | Q9H649 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10211140 | 0.79 | RAB9A (0.53) | STAT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11154084 | 0.79 | STAT3 (0.75) | STAT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2681128 | 0.78 | STAT3 (1.00) | STAT3RAB9ANPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL375506 | 0.78 | NPC1 (0.55) | STAT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL28478834 | 0.78 | STAT3 (1.00) | STAT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL29908282 | 0.78 | STAT3 (1.00) | STAT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL881752 | 0.77 | STAT3 (0.67) | STAT3RAB9ANPC1MEN1KMT2A | |
| Tenonitrozole SCHEMBL150446 | 0.77 | NPC1 (1.00) | STAT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL17732649 | 0.76 | NPC1 (0.68) | STAT3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL872527 | 0.76 | NPC1 (0.52) | STAT3RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632460-A2 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | University Of Virginia Patent Foundation (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012040170-A2 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-03-29 | — | — | WO | disclosed |