Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29156 | 0.90 | — | — | |
| SCHEMBL10608809 | 0.90 | — | — | |
| Ethylene SCHEMBL8677971 | 0.88 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Charcoal, Activated SCHEMBL11360977 | 0.88 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2641211 | 0.84 | TSHR (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Vinyl Chloride SCHEMBL10416733 | 0.84 | TSHR (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL3666285 | 0.84 | TSHR (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Toluene SCHEMBL10899737 | 0.84 | THRB (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Urethane SCHEMBL17965916 | 0.83 | ALOX15 (0.40) | TSHRHPGD | |
| Phosphoric Acid SCHEMBL16360251 | 0.82 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113271934-B | Composition for treating or preventing diabetic cataract | 高丽大学校产学协力团 | 2024-05-28 | — | — | CN | disclosed |
| US-11938166-B2 | Methods and compositions for treating mucosal tissue disorders | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-03-26 | — | — | US | disclosed |
| EP-4268843-A2 | IMPROVED IL-6 ANTIBODIES | F. Hoffmann-La Roche Ltd (CH) | 2023-11-01 | — | — | EP | disclosed |
| US-20220169719-A1 | IL-6 ANTIBODIES | Sesen Bio, Inc. | 2022-06-02 | — | — | US | disclosed |
| US-20220143129-A1 | METHODS AND COMPOSITIONS FOR TREATING MUCOSAL TISSUE DISORDERS | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2022-05-12 | — | — | US | disclosed |
| US-11154560-B2 | Methods for treating ocular inflammatory diseases | SUN PHARMA GLOBAL FZE (AE) | 2021-10-26 | — | — | US | disclosed |
| US-11142571-B2 | IL-6 antibodies | Sesen Bio, Inc. (US) | 2021-10-12 | — | — | US | disclosed |
| CN-113271934-A | Composition for treating or preventing diabetic cataract | 高丽大学校产学协力团 | 2021-08-17 | — | — | CN | disclosed |
| US-11058743-B2 | Methods and compositions for treating mucosal tissue disorders | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-07-13 | — | — | US | disclosed |
| US-20210205330-A1 | METHODS FOR TREATING OCULAR INFLAMMATORY DISEASES | SUN PHARMA GLOBAL FZE (AE) | 2021-07-08 | — | — | US | disclosed |
| EP-0536255-A4 | OPHTHALMIC SUSPENSIONS | — | 1993-07-07 | — | — | EP | disclosed |
| EP-0536255-A1 | OPHTHALMIC SUSPENSIONS. | INSITE VISION INC (US) | 1993-04-14 | — | — | EP | disclosed |
| US-5192535-A | Crosslinked polymers for delivery of drugs for eyes | INSITE VISION INCORPORATED (US) | 1993-03-09 | — | — | US | disclosed |
| WO-1992000044-A1 | OPHTHALMIC SUSPENSIONS | INSITE VISION INCORPORATED (US) | 1992-01-09 | — | — | WO | disclosed |
| EP-0362321-A4 | OPHTHALMIC SUSPENSIONS | — | 1991-05-08 | — | — | EP | disclosed |
| EP-0362321-A1 | OPHTHALMIC SUSPENSIONS. | INSITE VISION INC (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1989006964-A1 | OPHTHALMIC SUSPENSIONS | INSITE VISION, INC. (US) | 1989-08-10 | — | — | WO | disclosed |
| EP-0222878-A4 | AQUEOUS ALKALINE DEVELOPABLE, UV CURABLE URETHANE ACRYLATE COMPOUNDS AND COMPOSITIONS USEFUL FOR FORMING SOLDER MASK COATINGS. | M & T CHEMICALS INC (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0222878-A1 | AQUEOUS ALKALINE DEVELOPABLE, UV CURABLE URETHANE ACRYLATE COMPOUNDS AND COMPOSITIONS USEFUL FOR FORMING SOLDER MASK COATINGS. | M & T CHEMICALS INC (US) | 1987-05-27 | — | — | EP | disclosed |
| WO-1986006730-A1 | AQUEOUS ALKALINE DEVELOPABLE, UV CURABLE URETHANE ACRYLATE COMPOUNDS AND COMPOSITIONS USEFUL FOR FORMING SOLDER MASK COATINGS | M&T CHEMICALS, INC. (US) | 1986-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169719-A1 | IL-6 ANTIBODIES | IL6, IL6ST, IL2 | TSHR 1328/4885ALDH1A1 1783/4885TP53 3304/4885 |
| US-11142571-B2 | IL-6 antibodies | IL6, IL6ST, IL2 | TSHR 1245/4885ALDH1A1 1869/4885TP53 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.