SCHEMBL8764033

SCHEMBL8764033

Cc1cc(S(N)(=O)=O)cc(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.48
CA1 P00915 12/20 0.48
CA9 Q16790 11/20 0.48
CA12 O43570 7/20 0.48
CA3 P07451 3/20 0.48
CA6 P23280 3/20 0.48
CA5A P35218 3/20 0.48
CA7 P43166 3/20 0.48
CA5B Q9Y2D0 3/20 0.48
APEX1 P27695 2/20 0.46
CYP2C19 P33261 1/20 0.46
SOS1 Q07889 1/20 0.44
MAPT P10636 1/20 0.41
CA4 P22748 2/20 0.40
CA13 Q8N1Q1 2/20 0.40
CA14 Q9ULX7 2/20 0.40
POLB P06746 2/20 0.40
PLA2G7 Q13093 1/20 0.40
LMNA P02545 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28316697 0.86 CA1 (0.45) CA2CA1CA9CA12CA3
SCHEMBL27911417 0.82 CA1 (0.56) CA2CA1CA9CA12CA3
SCHEMBL28157363 0.80 CA2 (0.44) CA2CA1CA9CA12CA3
SCHEMBL8764095 0.80 CA2 (0.52) CA2CA1CA9CA12CA3
SCHEMBL9001244 0.78 GAA (0.43) CA2CA1MAPTPOLBLMNA
SCHEMBL6467893 0.77 CA2 (0.62) CA2CA1CA9CA12CA3
SCHEMBL10864491 0.77 CA1 (0.54) CA2CA1CA9CA12CA3
SCHEMBL9480049 0.77 CA1 (0.49) CA2CA1CA9CA12CA3
SCHEMBL8937977 0.76 LMNA (0.39) CA2CA1LMNATDP1HTT
SCHEMBL2005577 0.76 CA2 (0.56) CA2CA1CA9CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
CN-119219809-A Fluorine-containing polymer, preparation method thereof and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
EP-0550157-B1 Antitumor compositions and methods of treatment LILLY CO ELI (US) 1997-07-23 EP disclosed
US-5354778-A N-Phenyl-N'-substituted phenylsulfonylureas ELI LILLY AND COMPANY (US) 1994-10-11 US disclosed
US-5234955-A N-phenyl-N*-substituted phenylsulfonylureas ELI LILLY AND COMPANY (US) 1993-08-10 US disclosed
EP-0550157-A1 Antitumor compositions and methods of treatment ELI LILLY AND COMPANY (US) 1993-07-07 EP disclosed
US-4792628-A ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-12-20 US disclosed