SCHEMBL8937977

SCHEMBL8937977

Cc1cc(S([O])(=O)=O)cc(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.37
FFAR4 Q5NUL3 2/20 0.34
GAA P10253 2/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
CYP19A1 P11511 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9001244 0.80 GAA (0.43) LMNATDP1ALDH1A1FFAR4GAA
SCHEMBL15041660 0.78 LMNA (0.39) LMNATDP1ALDH1A1GAAMAPK1
SCHEMBL4324591 0.76 ALDH1A1 (0.40) LMNATDP1ALDH1A1FFAR4GAA
SCHEMBL84322 0.76 LCK (0.44) LMNATDP1ALDH1A1GAAMAPK1
SCHEMBL10664088 0.76 LMNA (0.38) LMNATDP1ALDH1A1FFAR4GAA
SCHEMBL8764033 0.76 CA2 (0.48) LMNATDP1HTTCA1CA2
SCHEMBL5872644 0.74 ALDH1A1 (0.38) ALDH1A1FFAR4GAAHTTKMT2A
SCHEMBL27341025 0.72 LMNA (0.35) LMNATDP1ALDH1A1FFAR4GAA
SCHEMBL25783730 0.71 LMNA (0.32) LMNATDP1
SCHEMBL13170230 0.70 ALDH1A1 (0.44) LMNATDP1ALDH1A1FFAR4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512061-A PRINTING PATTERNS ONTO FIBROUS SHEETS BY APPLYING AQUEOUS SOLUTION CONTAINING FIXING ALKALI AND PRETREATMENT COMPOUND THEN DYEING HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-30 US claimed
US-5578088-A Process for dyeing aminated cellulose/polyester blend fabric with fiber-reactive disperse dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-5575821-A Process for the preparation of a modified fiber material and process for the dyeing of the modified material with anionic textile dyes HOECHST AG (DE) 1996-11-19 US disclosed
US-5512061-A PRINTING PATTERNS ONTO FIBROUS SHEETS BY APPLYING AQUEOUS SOLUTION CONTAINING FIXING ALKALI AND PRETREATMENT COMPOUND THEN DYEING HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-30 US disclosed
US-5507840-A FIBERS MODIFIED WITH COMPOUND CONTAINING HYDROXY, AMINE AND AT LEAST ONE HYDROLYZABLE ESTER GROUPS HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
US-5348557-A Pretreatment of cotton fabric with amino compound, reduced water pollution HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-20 US disclosed
CN-1087694-A Use anionic textile dyes, on modified fiber materials, make the method for product dyed thereby with the ink jet printing technique HOECHST AG (DE) 1994-06-08 CN disclosed