Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | RAD1 | O60671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763679 | 0.80 | P2RY6 (0.47) | MIFCYP3A4P2RY6ALDH1A1MAPT | |
| SCHEMBL29444412 | 0.78 | MIF (0.50) | MIFCYP3A4P2RY6ALDH1A1MAPT | |
| SCHEMBL23558 | 0.77 | HTR3E (0.53) | MIFCYP3A4ALDH1A1MAPTMEN1 | |
| SCHEMBL29717662 | 0.76 | MPI (0.46) | MIFCYP3A4P2RY6ALDH1A1MAPT | |
| SCHEMBL6699663 | 0.76 | MPI (0.46) | MIFCYP3A4P2RY6ALDH1A1MAPT | |
| SCHEMBL2893673 | 0.75 | MIF (0.57) | MIFALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9857139 | 0.75 | MIF (0.47) | MIFCYP3A4P2RY6ALDH1A1MAPT | |
| SCHEMBL28866376 | 0.75 | MIF (0.52) | MIFCYP3A4P2RY6ALDH1A1MAPT | |
| SCHEMBL483888 | 0.74 | MIF (0.67) | MIFCYP3A4P2RY6ALDH1A1MAPT | |
| SCHEMBL6677730 | 0.74 | ENPP2 (0.41) | CYP3A4ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452858-B1 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INT BV (NL) | 1997-07-16 | — | — | EP | claimed |