Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444412 | 0.82 | MIF (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10818541 | 0.81 | HTR3E (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17707284 | 0.81 | HTR3E (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL23447 | 0.81 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29541540 | 0.81 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3085833 | 0.80 | CYP3A4 (0.49) | MIFCYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL5796149 | 0.80 | MIF (0.44) | MIFCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1021008 | 0.79 | ALDH1A1 (0.50) | MIFCYP3A4CYP1A2MAPTMEN1 | |
| SCHEMBL28866376 | 0.79 | MIF (0.52) | MIFCYP3A4CYP1A2TDP1MAPT | |
| SCHEMBL9857139 | 0.79 | MIF (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947780-B | Preparation method of thiazolidine-4-thioketone derivative | 华侨大学 | 2025-06-03 | — | — | CN | claimed |
| CN-117924210-A | Preparation method of 2-iminothiazolidine-4-ketone compound | 赣南师范大学 | 2024-04-26 | — | — | CN | claimed |
| EP-3383378-B1 | METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA) | PROCTER & GAMBLE (US) | 2024-04-17 | — | — | EP | claimed |
| CN-114751868-B | Diaryl substituted triazole acetic acid compound, and preparation method and application thereof | 山东理工大学 | 2024-04-12 | — | — | CN | claimed |
| CN-114516848-B | Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition | 万华化学集团股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116947780-A | Preparation method of thiazolidine-4-thioketone derivative | 华侨大学 | 2023-10-27 | — | — | CN | claimed |
| CN-114751868-A | Diaryl-substituted triazole acetic acid compound and preparation method and application thereof | 山东理工大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114516848-A | Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition | 万华化学集团股份有限公司 | 2022-05-20 | — | — | CN | claimed |
| EP-3383376-B1 | METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA) | PROCTER & GAMBLE (US) | 2021-05-12 | — | — | EP | claimed |
| CN-109265382-A | A kind of fluorine-containing thiocarbamates compound and its synthetic method | 湖北科技学院 | 2019-01-25 | — | — | CN | claimed |
| WO-2017095995-A1 | METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA) | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-08 | — | — | WO | claimed |
| US-20170151208-A1 | METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA) | THE CLEVELAND CLINIC FOUNDATION | 2017-06-01 | — | — | US | claimed |
| US-20170151250-A1 | METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA) | THE CLEVELAND CLINIC FOUNDATION | 2017-06-01 | — | — | US | claimed |
| CN-106045938-A | Synthesis method of dehydroabietic-acid-based B ring-fused-thiazole-thiocarbamide compounds | 广西大学 | 2016-10-26 | — | — | CN | claimed |
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| CN-103864655-B | A kind of synthetic method of dehydrogenation abietyl thiourea derivative | GUANGXI UNIVERSITY (CN) | 2015-12-30 | — | — | CN | claimed |
| CN-103864655-A | Synthetic method of dehydroabietic acid group thiourea derivative | UNIV GUANGXI | 2014-06-18 | — | — | CN | claimed |
| CN-101792440-B | Quinazolinone derivatives, preparation and application thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2011-12-28 | — | — | CN | claimed |
| CN-101792440-A | Quinazolinone derivatives, preparation and application thereof | UNIV EAST CHINA NORMAL | 2010-08-04 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | HTR3E 2361/4885HTR3B 2360/4885HTR3A 3106/4885 |
| US-20170151208-A1 | METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA) | HNMT, BHMT, PNMT | HTR3E 856/4885HTR3B 517/4885HTR3A 646/4885 |
| US-20170151250-A1 | METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA) | CRAT, CPT1A, CPT1B | HTR3E 1282/4885HTR3B 931/4885HTR3A 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.