Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 4/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384436 | 0.83 | KDM4E (0.43) | RENMMP1MMP2MMP9ACE | |
| SCHEMBL8763029 | 0.82 | ELANE (0.40) | LTA4HSLC7A5ANPEPRNPEPDNPEP | |
| SCHEMBL7384926 | 0.82 | ANPEP (0.44) | LTA4HANPEPRNPEPDNPEPREN | |
| SCHEMBL7763698 | 0.81 | ELANE (0.40) | ANPEPRNPEPDNPEPMMP1MMP2 | |
| SCHEMBL7382947 | 0.81 | ANPEP (0.43) | LTA4HANPEPRNPEPDNPEPREN | |
| SCHEMBL8764190 | 0.76 | MME (0.43) | RENMMP1MMP2MMP9FCER2 | |
| SCHEMBL8763008 | 0.76 | ANPEP (0.42) | LTA4HSLC7A5ANPEPRNPEPDNPEP | |
| SCHEMBL8764855 | 0.73 | MMP1 (0.48) | ANPEPRNPEPDNPEPRENMMP1 | |
| SCHEMBL27468737 | 0.73 | ANPEP (0.53) | LTA4HSLC7A5ANPEPRNPEPDNPEP | |
| SCHEMBL3489862 | 0.72 | ANPEP (0.47) | LTA4HSLC7A5ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | claimed |
| WO-1996011209-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | claimed |