Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472350 | 0.85 | ALDH1A1 (0.43) | L3MBTL1TSHRRAB9AKDM4EALDH1A1 | |
| SCHEMBL8907681 | 0.81 | ALDH1A1 (0.41) | L3MBTL1CYP1A2CYP2C19TSHRALDH1A1 | |
| SCHEMBL8891866 | 0.80 | KDM4E (0.45) | CYP1A2CYP2C19TSHRKDM4EALDH1A1 | |
| SCHEMBL8471428 | 0.79 | MAPT (0.49) | L3MBTL1TSHRRAB9AKDM4EALDH1A1 | |
| SCHEMBL8764485 | 0.78 | GRM2 (0.41) | L3MBTL1TSHRKDM4EALDH1A1MEN1 | |
| SCHEMBL8763820 | 0.78 | GRM2 (0.41) | L3MBTL1TSHRKDM4EALDH1A1MEN1 | |
| SCHEMBL8764408 | 0.78 | GRM2 (0.41) | L3MBTL1TSHRKDM4EALDH1A1MEN1 | |
| SCHEMBL8892774 | 0.77 | CA1 (0.48) | ATMTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL8892095 | 0.77 | TSHR (0.38) | CYP1A2CYP2C19TSHRKDM4EALDH1A1 | |
| SCHEMBL8764454 | 0.74 | MDM2 (0.36) | CYP1A2CYP2C19TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |