Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764485 | 0.84 | GRM2 (0.41) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8764408 | 0.84 | GRM2 (0.41) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8763820 | 0.84 | GRM2 (0.41) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8472350 | 0.82 | ALDH1A1 (0.43) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8471428 | 0.81 | MAPT (0.49) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8907681 | 0.79 | ALDH1A1 (0.41) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8891866 | 0.78 | KDM4E (0.45) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL8764221 | 0.77 | ATM (0.43) | ALDH1A1KDM4EHPGDTSHRATM | |
| SCHEMBL8764454 | 0.75 | MDM2 (0.36) | ALDH1A1KDM4EHTTLMNATSHR | |
| SCHEMBL8892095 | 0.73 | TSHR (0.38) | ALDH1A1KDM4EHTTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |