Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763820 | 1.00 | GRM2 (0.41) | GRM2GRM3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8764408 | 1.00 | GRM2 (0.41) | GRM2GRM3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8891866 | 0.85 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL8892774 | 0.84 | CA1 (0.48) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL8907681 | 0.80 | ALDH1A1 (0.41) | GRM2GRM3ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8472350 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL8764221 | 0.78 | ATM (0.43) | ALDH1A1KDM4EL3MBTL1TSHRMEN1 | |
| SCHEMBL8471428 | 0.77 | MAPT (0.49) | GRM2GRM3ALDH1A1KDM4ECA12 | |
| SCHEMBL8764454 | 0.76 | MDM2 (0.36) | ALDH1A1KDM4ESMN1; SMN2TSHRPOLB | |
| SCHEMBL8892095 | 0.73 | TSHR (0.38) | ALDH1A1KDM4ESMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |