SCHEMBL8764326

SCHEMBL8764326

CCN(c1nc(-c2ccccc2)c(C=O)s1)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CHEK1 O14757 1/20 0.33
KCNH2 Q12809 1/20 0.33
RORC P51449 1/20 0.33
SLC6A9 P48067 1/20 0.33
SLC6A5 Q9Y345 1/20 0.33
GSTO1 P78417 1/20 0.33
GBA1 P04062 3/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764226 0.73 ALDH1A1 (0.40) ALDH1A1HPGD
SCHEMBL18160546 0.71 ALDH1A1 (0.40) ALDH1A1
SCHEMBL13159130 0.71 ALDH1A1 (0.39) ALDH1A1NPC1RAB9AHSD17B10
SCHEMBL8768034 0.68 NPSR1 (0.42) ALDH1A1L3MBTL1NPC1RAB9AGBA1
SCHEMBL10280665 0.67 NTRK1 (0.51) ALDH1A1GSTO1
SCHEMBL11691432 0.67 L3MBTL1 (0.46) ALDH1A1L3MBTL1HPGDNPC1RAB9A
SCHEMBL3452395 0.66 KMT2A (0.40) ALDH1A1S1PR1S1PR3HPGDRORC
SCHEMBL3452147 0.66 KMT2A (0.45) HPGDRORCSLC6A9SLC6A5TRPM8
SCHEMBL5159959 0.65 MEN1 (0.47) ALDH1A1SLC6A9SLC6A5
SCHEMBL13109529 0.65 MEN1 (0.42) ALDH1A1HPGDSLC6A9SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654122-A HEAT SENSITIVE ELEMENTS BASF AKTIENGESELLSCHAFT (DE) 1997-08-05 US disclosed
EP-0582579-B1 N-AMINOPYRIDONE DYES BASF AG (DE) 1997-05-28 EP disclosed
US-5580980-A N-aminopyridone dyes BASF AKTIENGESELLSCHAFT (DE) 1996-12-03 US disclosed
EP-0582579-A1 N-AMINOPYRIDONE DYES. BASF AG (DE) 1994-02-16 EP disclosed
WO-1992019684-A1 N-AMINOPYRIDONE DYES BASF AKTIENGESELLSCHAFT (DE) 1992-11-12 WO disclosed