Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017611 | 0.78 | S1PR1 (0.42) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL8905979 | 0.71 | GBA1 (0.44) | ALDH1A1MEN1KMT2ATP53GBA1 | |
| SCHEMBL11691432 | 0.70 | L3MBTL1 (0.46) | HTTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11069272 | 0.68 | CHRM1 (0.46) | HTTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8764326 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GBA1NPC1RAB9AL3MBTL1 | |
| SCHEMBL4864061 | 0.67 | HTT (0.60) | NPSR1HTTALDH1A1MAPTMEN1 | |
| SCHEMBL27584294 | 0.66 | NPC1 (0.36) | ALDH1A1MAPTMEN1KMT2AGBA1 | |
| SCHEMBL4484272 | 0.64 | ADH1C (0.41) | NPSR1MEN1KMT2ATP53RAB9A | |
| SCHEMBL4474636 | 0.64 | ADH1C (0.41) | NPSR1MEN1KMT2ATP53RAB9A | |
| SCHEMBL16429035 | 0.64 | IDO1 (0.43) | NPSR1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682947-B1 | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia | MITSUBISHI CHEM CORP (JP) | 1997-09-10 | — | — | EP | claimed |
| US-5643911-A | CEREBROVASCULAR DISEASE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-01 | — | — | US | claimed |
| EP-0682947-A1 | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia | Mitsubishi Chemical Corporation (JP) | 1995-11-22 | — | — | EP | claimed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| EP-0682947-A1 | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia | Mitsubishi Chemical Corporation (JP) | 1995-11-22 | — | — | EP | disclosed |