Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 19/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764409 | 0.82 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL1368288 | 0.80 | VCAM1 (0.63) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL3209835 | 0.79 | VCAM1 (0.68) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL9805806 | 0.79 | VCAM1 (0.65) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL10048832 | 0.78 | VCAM1 (0.55) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL8763338 | 0.76 | SOS1 (0.41) | — | |
| SCHEMBL8763322 | 0.75 | CA1 (0.47) | ALDH1A1 | |
| SCHEMBL8897124 | 0.75 | VCAM1 (0.69) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL9404105 | 0.75 | VCAM1 (0.63) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL10452716 | 0.74 | VCAM1 (0.73) | VCAM1ALDH1A1NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | claimed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | claimed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |