Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960225 | 0.86 | FOLH1 (0.51) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL8758745 | 0.83 | FOLH1 (0.56) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL2553810 | 0.81 | FOLH1 (0.58) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL30354557 | 0.81 | FOLH1 (0.61) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL991080 | 0.81 | FOLH1 (0.61) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL371526 | 0.80 | FOLH1 (0.70) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL4871285 | 0.80 | FOLH1 (0.56) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL8759256 | 0.80 | ALDH1A1 (0.57) | TP53SMN1; SMN2RAB9AHIF1A | |
| SCHEMBL3387825 | 0.78 | FOLH1 (0.58) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL31124111 | 0.78 | FOLH1 (0.58) | FOLH1MRGPRX4TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664281-B1 | ISOCARBACYCLIN WITH MODIFIED alpha(a)-CHAIN AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 1997-05-28 | — | — | EP | disclosed |
| EP-0722725-A1 | VASCULAR SMOOTH MUSCLE CELL MIGRATION INHIBITOR | TEIJIN LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |
| EP-0664281-A1 | ISOCARBACYCLIN WITH MODIFIED $g(a)-CHAIN AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1995-07-26 | — | — | EP | disclosed |