SCHEMBL8764553

SCHEMBL8764553

O=c1cc(O)cc2oc3ccccc3cc1-2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.54
ALDH1A1 P00352 4/20 0.54
RAB9A P51151 3/20 0.54
GAPDH P04406 2/20 0.54
NPC1 O15118 1/20 0.54
ESR1 P03372 1/20 0.54
GAA P10253 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ESR2 Q92731 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
TDP1 Q9NUW8 2/20 0.54
LMNA P02545 1/20 0.53
TYR P14679 1/20 0.50
DAO P14920 1/20 0.50
AKR1B1 P15121 1/20 0.50
KDM4E B2RXH2 3/20 0.48
CYP3A4 P08684 3/20 0.48
CYP2C9 P11712 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764976 0.83 PTGS1 (0.58) HPGDALDH1A1RAB9ANPC1GAA
SCHEMBL6891938 0.80 KMT2A (0.48) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL8871524 0.80 MEN1 (0.50) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL30422441 0.78 HPGD (0.56) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL5941127 0.78 HPGD (0.56) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL21581946 0.77 MAOB (0.51) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL29715080 0.77 MAOB (0.51) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL6888526 0.76 KMT2A (0.44) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL30417366 0.75 RAB9A (0.68) HPGDALDH1A1RAB9AGAPDHNPC1
SCHEMBL28904480 0.74 RAB9A (0.67) HPGDALDH1A1RAB9AGAPDHNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330304-B1 PHOTOCURABLE RESIN COMPOSITION, FUEL CELL, AND SEALING METHOD THREE BOND CO LTD (JP) 2020-07-15 EP claimed
EP-0620918-B1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL (GB) 1997-07-30 EP claimed
EP-0105870-B1 MEASUREMENT DEVICE FOR DETERMINING THE CARBON DIOXIDE CONTENT OF A SAMPLE AVL AG (CH) 1987-02-11 EP disclosed
EP-0105870-A2 Measurement device for determining the carbon dioxide content of a sample AVL AG (CH) 1984-04-18 EP disclosed