Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731308 | 0.90 | MAPT (0.56) | MAPTALDH1A1GAAKDM4EEGFR | |
| SCHEMBL9731406 | 0.82 | KDM4E (0.50) | MAPTALDH1A1GAAKDM4EEGFR | |
| SCHEMBL8764571 | 0.80 | CCR1 (0.53) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL9732630 | 0.79 | MAPT (0.55) | MAPTALDH1A1GAAKDM4EEGFR | |
| SCHEMBL9322706 | 0.75 | EGFR (0.74) | MAPTALDH1A1GAAKDM4EEGFR | |
| SCHEMBL9322697 | 0.75 | EGFR (0.74) | MAPTALDH1A1GAAKDM4EEGFR | |
| SCHEMBL9730980 | 0.74 | EGFR (0.48) | MAPTALDH1A1GAAKDM4EEGFR | |
| Formamide SCHEMBL9730946 | 0.74 | TLR8 (0.40) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL9732353 | 0.72 | EGFR (0.49) | MAPTALDH1A1GAAKDM4EEGFR | |
| SCHEMBL9731149 | 0.72 | MAPT (0.46) | MAPTALDH1A1GAAKDM4EEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |