SCHEMBL8764065

SCHEMBL8764065

COOP(=O)(COS(=O)(=O)c1ccccc1Cl)OOC(C)C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.33
KCNH2 Q12809 1/20 0.32
NFE2L2 Q16236 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
F2 P00734 1/20 0.31
CTRC Q99895 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764166 0.95 HSD11B1 (0.33) HSD11B1KCNH2NFE2L2KDM4ECYP1A2
SCHEMBL8764592 0.89
SCHEMBL8764522 0.86 KMT2A (0.32)
SCHEMBL8763919 0.86 ALDH1A1 (0.37) KDM4EHTT
SCHEMBL8762833 0.84 HSD11B1 (0.35) HSD11B1KCNH2NFE2L2KDM4ECYP1A2
SCHEMBL8764573 0.82 MEN1 (0.34) HSD11B1F2
SCHEMBL8762722 0.82 NR3C1 (0.32)
SCHEMBL8734748 0.82 ALDH1A1 (0.36) HSD11B1KCNH2NFE2L2F2
SCHEMBL8762888 0.81 HTT (0.31) HSD11B1KDM4EF2HTT
SCHEMBL8764717 0.81 KMT2A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed