Methylamine

SCHEMBL8764733

CC(=O)SC(CCCCN1C(=O)c2ccccc2C1=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O.CN

nearest known ligand 0.51

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MMP3	P08254	11/20	0.51

▸	MMP1	P03956	8/20	0.51

▸	MMP2	P08253	7/20	0.50

▸	MMP9	P14780	7/20	0.50

▸	MMP7	P09237	3/20	0.50

▸	MMP14	P50281	3/20	0.50

▸	MME	P08473	1/20	0.42

▸	GNPAT	O15228	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7420233	0.98	MMP3 (0.52)	MMP3MMP1MMP2MMP9MMP7
Formamide SCHEMBL8764728	0.96	MMP3 (0.49)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL7419821	0.96	MMP3 (0.51)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL8387059	0.92	MMP1 (0.49)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL6411992	0.92	MMP1 (0.59)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL7894400	0.89	MMP1 (0.59)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL8387026	0.89	MMP1 (0.59)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL6413515	0.89	MMP1 (0.59)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL7452724	0.87	MMP1 (0.48)	MMP3MMP1MMP2MMP9MMP7
SCHEMBL6948615	0.87	MMP1 (0.48)	MMP3MMP1MMP2MMP9MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0784629-A1	PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES	Chiroscience Limited (GB)	1997-07-23	—	—	EP	claimed
WO-1996011209-A1	PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES	CHIROSCIENCE LIMITED (GB)	1996-04-18	—	—	WO	claimed