Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.44 |
| ▸ | MMP1 | P03956 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP7 | P09237 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 3/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764249 | 0.91 | MMP1 (0.45) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7897220 | 0.82 | MMP1 (0.56) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL8764718 | 0.80 | MMP1 (0.50) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7894438 | 0.79 | MMP1 (0.56) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7481783 | 0.76 | MMP1 (0.48) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7895353 | 0.76 | MMP1 (0.55) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7480288 | 0.75 | MMP1 (0.53) | MMP1CAPN1CTSKCTSLCTSB | |
| SCHEMBL7762274 | 0.75 | CTSK (0.42) | MMP3MMP2MMP1MMP9MMP7 | |
| SCHEMBL7424750 | 0.74 | MMP1 (0.46) | MMP3MMP2MMP1CAPN1CTSK | |
| SCHEMBL7420777 | 0.74 | MMP1 (0.41) | MMP3MMP2MMP1MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011209-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |