Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30027075 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPK1SRD5A2CYP2B6TDP1 | |
| SCHEMBL5765607 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPK1SRD5A2TDP1STS | |
| SCHEMBL30387165 | 0.85 | TSHR (0.53) | ALDH1A1MAPK1CYP2B6STSTSHR | |
| SCHEMBL786065 | 0.85 | TSHR (0.53) | ALDH1A1MAPK1CYP2B6STSTSHR | |
| SCHEMBL6173194 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPK1SRD5A2TDP1ALOX5 | |
| SCHEMBL7426544 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPK1SRD5A2TDP1ALOX5 | |
| SCHEMBL19691119 | 0.82 | CYP2B6 (0.39) | ALDH1A1MAPK1SRD5A2CYP2B6STS | |
| Terephthalic Acid SCHEMBL6682039 | 0.81 | KDM4E (0.45) | ALDH1A1MAPK1SRD5A2CYP2B6ALOX5 | |
| SCHEMBL27918004 | 0.81 | CA12 (0.49) | ALDH1A1MAPK1TDP1ALOX5KDM4E | |
| SCHEMBL6901672 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPK1SRD5A2TDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103764641-B | The tricyclic compound of fractional saturation and preparation and application thereof | 扎夫根股份有限公司 | 2016-10-26 | — | — | CN | claimed |
| CN-103249735-B | Tricyclic compounds and methods of making and using the same | ZAFGEN CORP. (US) | 2016-04-06 | — | — | CN | claimed |
| CN-103764641-A | Partially saturated tricyclic compounds and methods of making and using same | ZAFGEN CORP | 2014-04-30 | — | — | CN | claimed |
| CN-103249735-A | Tricyclic compounds and methods of making and using the same | ZAFGEN CORP | 2013-08-14 | — | — | CN | claimed |
| CN-114981263-B | Novel quercetin redox derivatives and use thereof as BET inhibitors | 贝诺生物有限公司 | 2024-12-24 | — | — | CN | disclosed |
| WO-2024080780-A1 | NOVEL INDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | 고려대학교 산학협력단 | 2024-04-18 | — | — | WO | disclosed |
| EP-4244371-A1 | PRODUCTION OF CANNABINOIDS/PHYTOCANNABINOIDS WITH A PLANT EXTRACT | Technische Universität Darmstadt (DE) | 2023-09-20 | — | — | EP | disclosed |
| US-20230053152-A1 | Novel Quercetin Redox Derivative And Use Thereof As BET Inhibitor | BENOBIO CO., LTD. (KR) | 2023-02-16 | — | — | US | disclosed |
| CN-114981263-A | Novel quercetin redox derivatives and use thereof as BET inhibitors | 贝诺生物有限公司 | 2022-08-30 | — | — | CN | disclosed |
| WO-2022101306-A1 | PRODUCTION OF CANNABINOIDS/PHYTOCANNABINOIDS WITH A PLANT EXTRACT | Technische Universität Darmstadt (DE) | 2022-05-19 | — | — | WO | disclosed |
| EP-3873451-A1 | CANNABINOID ANALOGS AND METHODS FOR THEIR PREPARATION | BayMedica, Inc. (US) | 2021-09-08 | — | — | EP | disclosed |
| WO-2021107656-A2 | NOVEL QUERCETIN REDOX DERIVATIVE AND USE THEREOF AS BET INHIBITOR | 주식회사 베노바이오 | 2021-06-03 | — | — | WO | disclosed |
| WO-2004039366-A1 | NICOTINIC ACETYLCHOLINE AGONISTS IN THE TREATMENT OF GLAUCOMA AND RETINAL NEUROPATHY | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-05-13 | — | — | WO | disclosed |
| WO-2003093267-A1 | 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-11-13 | — | — | WO | disclosed |
| US-20030130305-A1 | Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-07-10 | — | — | US | disclosed |
| WO-2003042210-A1 | AZABICYCLIC-PHENYL-FUSED-HETEROCYCLIC COMPOUNDS AND THEIR USE AS ALPHA7 NACHR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-22 | — | — | WO | disclosed |
| EP-1109807-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-06-27 | — | — | EP | disclosed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | disclosed |
| WO-2000014087-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-03-16 | — | — | WO | disclosed |
| CN-1084170-A | Pyrazole derivatives | IDEMITSU KOSAN CO (JP) | 1994-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130305-A1 | Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease | TPMT, PAICS, MALT1 | ALDH1A1 144/4885MAPK1 3474/4885SRD5A2 147/4885 |
| US-20230053152-A1 | Novel Quercetin Redox Derivative And Use Thereof As BET Inhibitor | BET1, BRD4, BRD3 | ALDH1A1 3281/4885MAPK1 1643/4885SRD5A2 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.