SCHEMBL6901672

SCHEMBL6901672

O=C1C=Cc2cc(C(=O)O)ccc2OC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
MAPK1 P28482 1/20 0.49
SRD5A2 P31213 1/20 0.41
RARA P10276 3/20 0.39
RARG P13631 3/20 0.39
GAA P10253 4/20 0.39
MAPT P10636 3/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
CA9 Q16790 2/20 0.39
KDM4E B2RXH2 2/20 0.39
POLB P06746 1/20 0.39
CA6 P23280 1/20 0.39
PTGS2 P35354 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6109340 0.86 KDM4E (0.46) ALDH1A1MAPTKDM4EPOLBTSHR
SCHEMBL6107049 0.83 ALDH1A1 (0.47) ALDH1A1MAPK1SRD5A2RARARARG
SCHEMBL6109855 0.82 CA12 (0.50) ALDH1A1MAPK1GAAMAPTCA12
SCHEMBL6105961 0.82 ALOX5 (0.40) ALDH1A1GAAALOX5TSHRHPGD
SCHEMBL6901858 0.80 ALDH1A1 (0.45) ALDH1A1MAPK1SRD5A2RARARARG
SCHEMBL876479 0.80 ALDH1A1 (0.51) ALDH1A1MAPK1SRD5A2RARARARG
SCHEMBL30027075 0.80 ALDH1A1 (0.51) ALDH1A1MAPK1SRD5A2RARARARG
SCHEMBL6107430 0.79 ALDH1A1 (0.44) ALDH1A1MAPK1SRD5A2RARARARG
SCHEMBL6107433 0.79 ALDH1A1 (0.44) ALDH1A1MAPK1SRD5A2RARARARG
SCHEMBL7426544 0.76 ALDH1A1 (0.55) ALDH1A1MAPK1SRD5A2RARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1417197-A1 FUNGICIDAL 1-BENZOXEPIN DERIVATIVES Bayer CropScience S.A. (FR) 2004-05-12 EP disclosed
WO-2003014104-A1 FUNGICIDAL 1-BENZOXEPIN DERIVATIVES BAYER CROPSCIENCE SA (FR) 2003-02-20 WO disclosed