Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876479 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPK1TDP1SRD5A2KDM4E | |
| SCHEMBL30027075 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPK1TDP1SRD5A2KDM4E | |
| SCHEMBL6901672 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPK1TDP1SRD5A2KDM4E | |
| SCHEMBL28804341 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPK1TDP1SRD5A2KDM4E | |
| SCHEMBL5765607 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPK1TDP1SRD5A2KDM4E | |
| SCHEMBL6107049 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPK1TDP1SRD5A2KDM4E | |
| Piperonylic Acid SCHEMBL31119409 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPK1SRD5A2KDM4EMAPT | |
| SCHEMBL619634 | 0.71 | MAPK1 (0.78) | ALDH1A1MAPK1SRD5A2KDM4EMAPT | |
| Piperonylic Acid SCHEMBL142318 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPK1SRD5A2KDM4EMAPT | |
| Piperonylic Acid SCHEMBL3946119 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPK1SRD5A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |