Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.59 |
| ▸ | GSK3A | P49840 | 4/20 | 0.59 |
| ▸ | GSK3B | P49841 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | WRN | Q14191 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828559 | 0.79 | ALDH1A1 (0.49) | MGLLGSK3AGSK3BTSHRALDH1A1 | |
| SCHEMBL12769594 | 0.77 | ELANE (0.53) | MGLLGSK3AGSK3BTSHRFAAH | |
| SCHEMBL8062425 | 0.75 | GSK3A (0.63) | GSK3AGSK3BTSHRALDH1A1MAPK1 | |
| SCHEMBL145760 | 0.75 | MGLL (0.56) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL11062218 | 0.74 | ALDH1A1 (0.58) | MGLLGSK3AGSK3BTSHRFAAH | |
| SCHEMBL25435490 | 0.74 | MGLL (1.00) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| Benzoquinone SCHEMBL8469988 | 0.74 | TSHR (0.71) | TSHRALDH1A1MAPK1MAOAMAOB | |
| SCHEMBL207740 | 0.74 | MGLL (1.00) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL5225296 | 0.73 | MGLL (0.50) | MGLLGSK3AGSK3BTSHRFAAH | |
| SCHEMBL14686924 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1MAPK1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015350-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2026-01-15 | — | — | US | disclosed |
| EP-4540255-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| WO-2023244615-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| EP-0601974-B1 | Positive photoresist with better properties | OCG MICROELECTRONIC MATERIALS (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5558978-A | Photoresist compositions containing copolymers having acid-labile groups and recurring units derived from either N-(hydroxymethyl)maleimide or N-(acetoxymethyl)maleimide or both | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0659781-A2 | Copolymers of maleimide, for photoresists | OCG Microelectronic Materials Inc. (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5397680-A | Light sensitive elements with maleimide monomers and styrene derivatives polymers | CIBA-GEIGY AG (CH) | 1995-03-14 | — | — | US | disclosed |
| US-5369200-A | Positive photoresist having improved processing properties | CIBA-GEIGY AG (CH) | 1994-11-29 | — | — | US | disclosed |
| EP-0601974-A1 | Positive photoresist with better properties | OCG Microelectronic Materials Inc. (US) | 1994-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015350-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | KRAS, NRAS, HRAS | MGLL 4310/4885GSK3A 1615/4885GSK3B 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.