Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864517 | 0.86 | GSK3A (0.61) | GSK3AGSK3BTSHRHTTALDH1A1 | |
| SCHEMBL1401654 | 0.82 | GSK3A (0.56) | GSK3AGSK3BTSHRHTTALDH1A1 | |
| SCHEMBL3318940 | 0.78 | GSK3A (1.00) | GSK3AGSK3BTSHRALDH1A1KMT2A | |
| SCHEMBL7337661 | 0.77 | GSK3A (0.57) | GSK3AGSK3BTSHRALDH1A1LMNA | |
| SCHEMBL6283032 | 0.76 | GSK3A (0.56) | GSK3AGSK3BTSHRALDH1A1MAPK1 | |
| SCHEMBL8764825 | 0.75 | MGLL (0.59) | GSK3AGSK3BTSHRALDH1A1MAPK1 | |
| SCHEMBL20339321 | 0.75 | GSK3A (0.69) | GSK3AGSK3BTSHRHTTALDH1A1 | |
| SCHEMBL15264534 | 0.73 | GSK3A (0.53) | GSK3AGSK3BTSHRHTTALDH1A1 | |
| SCHEMBL17160682 | 0.72 | TSHR (0.46) | GSK3AGSK3BTSHRALDH1A1LMNA | |
| SCHEMBL5828559 | 0.71 | ALDH1A1 (0.49) | GSK3AGSK3BTSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560581-B1 | Process for producing 3-hydroxymethyl-1-propargyl-imidazolidine-2,4-dione | SUMITOMO CHEMICAL CO (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5767140-A | USEFUL FOR TREATING AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1998-06-16 | — | — | US | disclosed |
| US-5350859-A | Process for producing 3-hydroxymethyl-1-propargylimidazolidine-2,4-dione | SUMOTOMO CHEMICAL COMPANY, LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0560581-A2 | Process for producing 3-hydroxymethyl-1-propargyl-imidazolidine-2,4-dione | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |