SCHEMBL8764916

SCHEMBL8764916

Clc1ccc2c(Cl)ccc3c2c1C=C3

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TYMS P04818 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3408215 0.74 CYP1A2 (0.48) CYP1A2CYP2A6TYMS
SCHEMBL8765442 0.72 CYP1A2 (0.36) CYP1A2CYP2A6TYMS
SCHEMBL5039138 0.70 ALDH1A1 (0.40) CYP1A2CYP2A6
SCHEMBL8765414 0.69 CYP1A2 (0.32) CYP1A2CYP2A6
SCHEMBL8766049 0.67 CYP1A2 (0.33) CYP1A2CYP2A6
SCHEMBL3754754 0.66 MAPT (0.47) CYP1A2CYP2A6TYMS
SCHEMBL28481519 0.64 CYP1A2 (0.45) CYP1A2CYP2A6TYMS
SCHEMBL30679144 0.64 CYP1A2 (0.45) CYP1A2CYP2A6TYMS
SCHEMBL8765531 0.64
SCHEMBL6076850 0.62 CYP1A2 (0.58) CYP1A2CYP2A6TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed