Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764977 | 0.87 | CYSLTR2 (0.53) | IDO1FFAR1MAOA | |
| SCHEMBL17912813 | 0.85 | CYP11B1 (0.56) | CYP11B1CYP11B2NPC1RAB9AIDO1 | |
| SCHEMBL749033 | 0.79 | MAPT (0.59) | NPC1HTR1ADRD2 | |
| SCHEMBL10746907 | 0.78 | ALDH1A1 (0.59) | RAB9AHTR1ADRD2 | |
| SCHEMBL1558065 | 0.77 | ALDH1A1 (0.71) | CYP11B1CYP11B2NPC1RAB9AIDO1 | |
| SCHEMBL7055886 | 0.77 | ALDH1A1 (0.43) | NPC1RAB9A | |
| SCHEMBL12301146 | 0.76 | SCN4A (0.53) | CYP11B1CYP11B2NPC1RAB9AIDO1 | |
| SCHEMBL1928833 | 0.76 | LMNA (0.57) | CYP11B1CYP11B2NPC1RAB9AIDO1 | |
| SCHEMBL19612224 | 0.76 | MAPT (0.66) | CYP11B1CYP11B2NPC1RAB9AIDO1 | |
| SCHEMBL19612640 | 0.76 | HPGD (0.52) | CYP11B1CYP11B2NPC1RAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |