Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339812 | 0.84 | MAPT (0.71) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL23258867 | 0.83 | MAPT (0.59) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| Formaldehyde SCHEMBL27831678 | 0.82 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL8130463 | 0.80 | HTR1A (0.61) | MAPK1HTR1ADRD2LTA4HMAPK14 | |
| SCHEMBL8764941 | 0.79 | CYP11B1 (0.49) | HTR1ADRD2NPC1 | |
| SCHEMBL2096056 | 0.79 | ALOX5 (0.58) | MAPTL3MBTL1LMNANPC1 | |
| SCHEMBL13434101 | 0.78 | HTR1A (0.74) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL5538708 | 0.77 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL26013299 | 0.77 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL8216313 | 0.77 | MAPT (0.69) | MAPTMAPK1TDP1L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721546-A | Substituted pyrimidine aryl ester derivative and preparation method thereof, Herbicidal combinations and application | 青岛清原化合物有限公司 | 2019-05-07 | — | — | CN | claimed |
| CN-108753182-A | A kind of OCA optical cements haveing excellent performance, optical adhesive tape and preparation method thereof | 广东东立新材料科技股份有限公司 | 2018-11-06 | — | — | CN | claimed |
| EP-1465869-B1 | MODULATORS OF LXR | EXELIXIS PATENT CO LLC (US) | 2013-05-15 | — | — | EP | claimed |
| US-8044082-B2 | N-phenylacetamide inhibitors of the enzyme SOAT-1 and pharmaceutical/cosmetic compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-10-25 | — | — | US | claimed |
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | claimed |
| US-7547749-B2 | Triazine compounds, polymers comprising triazine structural units, and method | SABIC INNOVATIVE PLATICS IP B.V. (NL) | 2009-06-16 | — | — | US | claimed |
| CN-101239954-A | Triazine compounds and triazine compounds polymers comprising triazine structural units, and processes for the preparation of these polymers | GEN ELECTRIC (US) | 2008-08-13 | — | — | CN | claimed |
| US-20080097040-A1 | TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-04-24 | — | — | US | claimed |
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | ASTELLAS PHARMA GMBH (DE) | 2007-09-20 | — | — | US | claimed |
| EP-1465869-A4 | MODULATORS OF LXR | X CEPTOR THERAPEUTICS INC (US) | 2005-12-28 | — | — | EP | claimed |
| EP-0501986-A1 | ISOXAZOLINES, METHOD OF PREPARATION THEREOF, AND THEIR USE AS PLANT-PROTECTION AGENTS | Hoechst Schering AgrEvo GmbH (DE) | 1992-09-09 | — | — | EP | claimed |
| WO-1992003053-A1 | PLANT PROTECTING AGENTS CONTAINING ISOXAZOLINE OR ISOTHIAZOLINE AND NEW ISOXAZOLINES AND ISOTHIAZOLINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-05 | — | — | WO | claimed |
| CN-1059072-A | Contain the plant protection preparation of different azoles quinoline or isothiazoline and new different azoles quinoline class and isothiazoline compounds | HOECHST AG (DE) | 1992-03-04 | — | — | CN | claimed |
| CN-1058968-A | Plant protection product, its preparation method and application | HOECHST AG (DE) | 1992-02-26 | — | — | CN | claimed |
| WO-1991018907-A1 | PLANT-PROTECTING SUBSTITUTED ISOXAZOLINES, ISOXAZOLES, ISOTHIAZOLINES AND ISOTHIAZOLES, PROCESS FOR PRODUCING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-12 | — | — | WO | claimed |
| CN-1052308-A | Different azoles quinoline, its preparation method and as the application of plant protection product | HOECHST AG (DE) | 1991-06-19 | — | — | CN | claimed |
| WO-1991008202-A1 | ISOXAZOLINES, METHOD OF PREPARATION THEREOF, AND THEIR USE AS PLANT-PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-13 | — | — | WO | claimed |
| US-4713471-A | REACTING BENZYLOXYPHENOLS WITH HALOBUTANONES AND THEN WITH DIALKYL CARBONATES | STAUFFER CHEMICAL COMPANY (US) | 1987-12-15 | — | — | US | claimed |
| EP-0118685-A1 | Propene derivatives and their use as plant growth inhibitors | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-09-19 | — | — | EP | claimed |
| EP-0117412-A1 | Propene derivatives and their use as plant growth inhibitors | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-09-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | NFATC1, PDCD1, ACIN1 | MAPT 4047/4885MAPK1 1530/4885TDP1 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.