SCHEMBL8765073

SCHEMBL8765073

CCc1ccc(N(c2cccc(CC)c2)c2cc(C)cc(N(c3ccc(CC)cc3)c3cccc(CC)c3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.41
SIGMAR1 Q99720 14/20 0.40
POLB P06746 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766587 0.91 TP53 (0.44) SIGMAR1TP53CYP1A2CYP2A6
SCHEMBL13136831 0.88 SIGMAR1 (0.42) RAPGEF4SIGMAR1POLB
SCHEMBL13479421 0.88 SIGMAR1 (0.42) RAPGEF4SIGMAR1POLB
SCHEMBL13136832 0.86 CYP2C19 (0.44) RAPGEF4SIGMAR1TP53
SCHEMBL21392008 0.86 CYP2C19 (0.44) RAPGEF4SIGMAR1TP53
SCHEMBL13136833 0.86 POLB (0.47) SIGMAR1POLBTP53
SCHEMBL20030125 0.86 SIGMAR1 (0.43) RAPGEF4SIGMAR1POLB
SCHEMBL8765716 0.86 SIGMAR1 (0.47) SIGMAR1TP53
SCHEMBL25770671 0.85 SIGMAR1 (0.46) RAPGEF4SIGMAR1POLBTP53CYP1A2
SCHEMBL1858399 0.83 BCL2 (0.41) RAPGEF4SIGMAR1POLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420207-B1 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO LTD (JP) 1997-08-13 EP disclosed
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
US-5185228-A Binder resin, charge transfer material; stability MITA INDUSTRIAL CO., LTD. (JP) 1993-02-09 US disclosed
US-5128229-A Polycarbonate, m-phenylenediamine derivative MITA INDUSTRIAL CO., LTD. (JP) 1992-07-07 US disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0420207-A2 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO. LTD. (JP) 1991-04-03 EP disclosed
EP-0413338-A1 Electrophotosensitive material MITA INDUSTRIAL CO. LTD. (JP) 1991-02-20 EP disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed