Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 6/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765277 | 1.00 | CASP1 (0.57) | CASP1CTSKTACR1ALDH1A1MEN1 | |
| SCHEMBL15254319 | 0.92 | CASP1 (0.50) | CASP1CTSKTACR1ALDH1A1MEN1 | |
| SCHEMBL5408318 | 0.92 | CASP1 (0.50) | CASP1CTSKTACR1ALDH1A1MEN1 | |
| SCHEMBL8224981 | 0.92 | KYNU (0.59) | CASP1CTSKALDH1A1MEN1HPGD | |
| SCHEMBL6849362 | 0.91 | FOLH1 (0.58) | CASP1CTSKTACR1PPARGPPARA | |
| SCHEMBL7373019 | 0.91 | FOLH1 (0.58) | CASP1CTSKTACR1PPARGPPARA | |
| SCHEMBL11893028 | 0.91 | FOLH1 (0.58) | CASP1CTSKTACR1PPARGPPARA | |
| SCHEMBL14102865 | 0.90 | FOLH1 (0.54) | CASP1CTSKALDH1A1MEN1HPGD | |
| SCHEMBL2921260 | 0.90 | FOLH1 (0.59) | CASP1CTSKTACR1CTRB1CTSL | |
| SCHEMBL7624700 | 0.90 | FOLH1 (0.59) | CASP1CTSKTACR1CTRB1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624599-B1 | Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| US-5631244-A | PREPARATION OF INCLUSION COMPLEXES TO SOLUBILIZE COSMETIC AND DERMATOLOGICALLY ACTIVE MATERIALS | L'OREAL (FR) | 1997-05-20 | — | — | US | disclosed |