Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 5/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185940 | 0.77 | GRIN2B (0.86) | GRIN2BDRD2DRD3HDAC8 | |
| SCHEMBL8765336 | 0.77 | GRIN2B (0.48) | GRIN2BDRD2HDAC8PNMTADRA2A | |
| Hydrochloric Acid SCHEMBL8187601 | 0.76 | GRIN2B (0.84) | GRIN2BDRD2DRD3HDAC8 | |
| SCHEMBL4107613 | 0.75 | MTNR1A (0.62) | GRIN2BDRD2DRD3DRD4HDAC8 | |
| SCHEMBL4107609 | 0.75 | MTNR1A (0.62) | GRIN2BDRD2DRD3DRD4HDAC8 | |
| SCHEMBL12670596 | 0.74 | GRIN2B (0.61) | GRIN2BDRD2HDAC8PNMTADRA2A | |
| SCHEMBL8192687 | 0.73 | GRIN2B (0.67) | GRIN2BHDAC8 | |
| SCHEMBL6256301 | 0.73 | GRIN2B (0.52) | GRIN2BDRD3PNMTADRA2AADRA2B | |
| SCHEMBL8765338 | 0.72 | GRIN2B (0.46) | GRIN2BDRD2DRD3DRD4PNMT | |
| SCHEMBL23196100 | 0.72 | PNMT (0.54) | GRIN2BPNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |