Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 7/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765343 | 0.77 | GRIN2B (0.57) | GRIN2BHDAC8PNMTADRA2AADRA2B | |
| SCHEMBL4736395 | 0.75 | GRIN2B (0.48) | GRIN2BHDAC8PNMTADRA2AADRA2B | |
| SCHEMBL4736399 | 0.75 | GRIN2B (0.48) | GRIN2BHDAC8PNMTADRA2AADRA2B | |
| SCHEMBL12670596 | 0.74 | GRIN2B (0.61) | GRIN2BHDAC8PNMTADRA2AADRA2B | |
| SCHEMBL4107613 | 0.73 | MTNR1A (0.62) | GRIN2BHDAC8PNMTADRA2AADRA2B | |
| SCHEMBL4107609 | 0.73 | MTNR1A (0.62) | GRIN2BHDAC8PNMTADRA2AADRA2B | |
| SCHEMBL23196100 | 0.73 | PNMT (0.54) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL9359482 | 0.72 | MTNR1A (0.44) | GRIN2BHDAC8CRHBPCRHR2 | |
| SCHEMBL9716393 | 0.71 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2062472 | 0.71 | GRIN2B (0.64) | GRIN2BHDAC8PNMTADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583485-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |