SCHEMBL8765428

SCHEMBL8765428

C[Si](C)(C)c1cccc2c1C=CC2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2970461 0.75
SCHEMBL319418 0.74 CYP2A6 (0.35) CA1CA2
SCHEMBL15863762 0.73 PTAFR (0.33)
SCHEMBL6454972 0.72 CA1 (0.35) CA1CA2
SCHEMBL277191 0.71 CA1 (0.33) CA1CA2
SCHEMBL6909918 0.71 GABRA1 (0.41) CA1CA2
SCHEMBL7186336 0.71 CA1 (0.32) CA1CA2
SCHEMBL2958426 0.71
SCHEMBL277192 0.70 BCL2L1 (0.39) CA1CA2
SCHEMBL2783384 0.70 CA1 (0.32) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed