Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 1/20 | 0.55 |
| ▸ | YAP1 | P46937 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766135 | 1.00 | MEN1 (0.59) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL14032531 | 0.92 | HDAC8 (0.57) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL7302031 | 0.92 | ALDH1A1 (0.59) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL7351628 | 0.91 | HDAC8 (0.58) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL3350988 | 0.91 | BCL2 (0.64) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL6161729 | 0.91 | BCL2 (0.64) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL3500186 | 0.91 | BCL2 (0.64) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL31725913 | 0.90 | HDAC8 (0.55) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL24899403 | 0.87 | ITGB3 (0.59) | MEN1ALDH1A1LMNAKMT2AHDAC8 | |
| SCHEMBL8336016 | 0.87 | ITGB3 (0.59) | MEN1ALDH1A1LMNAKMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624599-B1 | Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| US-5631244-A | PREPARATION OF INCLUSION COMPLEXES TO SOLUBILIZE COSMETIC AND DERMATOLOGICALLY ACTIVE MATERIALS | L'OREAL (FR) | 1997-05-20 | — | — | US | disclosed |