SCHEMBL8765647

SCHEMBL8765647

Cc1cc(O)n(-c2ccc(C(=O)O)cc2)c(=O)c1C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
MAPT P10636 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
POLB P06746 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 1/20 0.47
APEX1 P27695 1/20 0.47
PTGES O14684 1/20 0.47
ALOX5 P09917 1/20 0.47
DUSP3 P51452 1/20 0.47
MCL1 Q07820 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAPK1 P28482 2/20 0.45
MYC P01106 2/20 0.42
DDAH1 O94760 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11424441 0.92 BRD4 (0.43) ALDH1A1KMT2AMEN1MAPTTDP1
SCHEMBL4651066 0.87 KDM4E (0.46) ALDH1A1KMT2AMEN1MAPTPOLB
SCHEMBL8985005 0.85 ALDH1A1 (0.54) ALDH1A1KMT2AMEN1MAPTTDP1
SCHEMBL11441344 0.83 RAB9A (0.56) ALDH1A1KMT2AMAPTPOLBKDM4E
SCHEMBL11409092 0.81 CA1 (0.39) ALDH1A1KMT2AMEN1MAPTL3MBTL1
SCHEMBL11427444 0.78 BRD4 (0.44) ALDH1A1KMT2AMEN1MAPTTDP1
SCHEMBL8765255 0.78 LMNA (0.56) ALDH1A1KMT2AMEN1MAPTTDP1
SCHEMBL9322999 0.76 KDM4E (0.45) ALDH1A1KMT2AMEN1TDP1POLB
SCHEMBL11437497 0.74 LMNA (0.55) ALDH1A1KMT2AMEN1KDM4EHPGD
SCHEMBL11421181 0.74 BRD4 (0.41) ALDH1A1KMT2AMEN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460550-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1997-08-06 EP disclosed
EP-0460550-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-12-11 EP disclosed