Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.59 |
| ▸ | LTA4H | P09960 | 4/20 | 0.52 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477011 | 0.78 | ESR1 (0.65) | ESR1ESR2LTA4HLMNAHIF1A | |
| SCHEMBL24628864 | 0.77 | SLC6A2 (0.44) | ESR1ESR2SLC6A2SLC6A3APP | |
| SCHEMBL8765685 | 0.77 | ESR1 (0.41) | ESR1ESR2LTA4HKDM4EALDH1A1 | |
| SCHEMBL1477066 | 0.77 | KDM4E (0.69) | ESR1ESR2LTA4HNR5A1KDM4E | |
| SCHEMBL12456886 | 0.76 | LTA4H (0.53) | ESR1ESR2LTA4HLMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL10806159 | 0.75 | KDM4E (0.67) | ESR1ESR2LTA4HNR5A1KDM4E | |
| SCHEMBL23475011 | 0.74 | ESR1 (0.40) | ESR1ESR2LTA4HHIF1AKDM4E | |
| SCHEMBL24312923 | 0.74 | KMT2A (0.45) | ESR1ESR2LMNAMEN1KMT2A | |
| SCHEMBL8995206 | 0.74 | ESR1 (0.40) | ESR1ESR2LTA4HCYP1A2CYP2C19 | |
| 1-Hydroxy-4-Ethoxybenzene SCHEMBL12476725 | 0.73 | LTA4H (0.86) | LTA4HNR5A1LMNAHIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |