Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995206 | 0.78 | ESR1 (0.40) | ESR1ESR2CXCR1KDM4EALDH1A1 | |
| SCHEMBL24628864 | 0.77 | SLC6A2 (0.44) | ESR1ESR2CXCR1KDM4EALDH1A1 | |
| SCHEMBL8765689 | 0.77 | ESR1 (0.59) | ESR1ESR2KDM4EALDH1A1LTA4H | |
| SCHEMBL8995211 | 0.77 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12456886 | 0.76 | LTA4H (0.53) | ESR1ESR2CXCR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23475011 | 0.74 | ESR1 (0.40) | ESR1ESR2CXCR1KDM4EALDH1A1 | |
| SCHEMBL24312923 | 0.74 | KMT2A (0.45) | ESR1ESR2CXCR1KDM4ESMN1; SMN2 | |
| SCHEMBL1199059 | 0.73 | NQO1 (0.74) | KDM4EALDH1A1SMN1; SMN2NQO1LTA4H | |
| SCHEMBL5311063 | 0.73 | ESR1 (0.38) | ESR1ESR2CXCR1KDM4EALDH1A1 | |
| SCHEMBL12678527 | 0.71 | NPC1 (0.59) | KDM4EALDH1A1SMN1; SMN2KEAP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |