Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | PRCP | P42785 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994152 | 0.95 | SIGMAR1 (0.56) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL4503607 | 0.88 | GRIN1 (0.46) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL7583601 | 0.77 | POLB (0.41) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL29348806 | 0.77 | HSD11B1 (0.52) | ALDH1A1L3MBTL1KMT2AHSD11B1 | |
| SCHEMBL7489860 | 0.75 | GRIN1 (0.71) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL7493298 | 0.75 | GRIN1 (0.71) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL7095191 | 0.75 | GRIN1 (0.71) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| SCHEMBL9153279 | 0.74 | SIGMAR1 (1.00) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| Rolicyclidine SCHEMBL517928 | 0.74 | SIGMAR1 (1.00) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D | |
| Phencyclidine SCHEMBL17008793 | 0.74 | SIGMAR1 (1.00) | GRIN1GRIN2ASIGMAR1GRIN2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112040958-A | Peptide-containing formulations | 科巴公司 | 2020-12-04 | — | — | CN | disclosed |
| EP-0787116-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | Akzo Nobel N.V. (NL) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011894-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | AKZO NOBEL N.V. (NL) | 1996-04-25 | — | — | WO | disclosed |
| US-4118393-A | Phenyl azabicyclohexanones | AMERICAN CYANAMID COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4118393-A | Phenyl azabicyclohexanones | AMERICAN CYANAMID COMPANY (US) | 1978-10-03 | — | — | US | disclosed |