SCHEMBL8765715

SCHEMBL8765715

CCCc1ccc(-c2c(N)cccc2N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RAB9A P51151 5/20 0.45
NPC1 O15118 3/20 0.45
GFER P55789 1/20 0.45
CA2 P00918 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 2/20 0.40
PKM P14618 1/20 0.40
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
HSD11B1 P28845 2/20 0.38
KDM4E B2RXH2 2/20 0.37
USP2 O75604 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509252 0.79 NPC1 (0.41) MAPTMEN1ALDH1A1KMT2ANPSR1
SCHEMBL4908052 0.79 HSD11B1 (0.45) MAPTMEN1ALDH1A1KMT2ARAB9A
SCHEMBL9842774 0.78 MAPT (0.47) MAPTMEN1ALDH1A1KMT2ANPSR1
SCHEMBL24254918 0.78 CYP3A4 (0.47) MEN1ALDH1A1KMT2ASMN1; SMN2HSD17B10
SCHEMBL4621460 0.76 SKP2 (0.56) MAPTMEN1ALDH1A1KMT2ARAB9A
SCHEMBL4802707 0.75 LPL (0.54) MAPTRAB9ANPC1GFERCA2
Benzidine SCHEMBL29111120 0.74 GFER (0.59) MAPTMEN1ALDH1A1KMT2ARAB9A
SCHEMBL1696232 0.74 GFER (0.59) MAPTMEN1ALDH1A1KMT2ARAB9A
SCHEMBL19253102 0.73 HTR2A (0.58) MAPTMEN1ALDH1A1KMT2ARAB9A
SCHEMBL9559509 0.72 LPL (0.43) MAPTMEN1ALDH1A1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420207-B1 Electrophotosensitive material and method of manufacturing the same MITA INDUSTRIAL CO LTD (JP) 1997-08-13 EP disclosed