Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 13/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223212 | 0.81 | TSHR (0.62) | TSHRTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8765726 | 0.79 | TSHR (0.46) | TSHRTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL2002013 | 0.79 | L3MBTL1 (0.65) | TDP1ALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL3814694 | 0.79 | ACHE (0.59) | TDP1ALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL14764174 | 0.77 | L3MBTL1 (0.47) | TSHRTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7639935 | 0.76 | TSHR (0.60) | TSHRTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7641709 | 0.76 | KDM4E (0.69) | TDP1ALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL6742429 | 0.75 | TSHR (0.58) | TSHRTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9213101 | 0.75 | TSHR (0.58) | TSHRTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL23142265 | 0.74 | TSHR (0.50) | TSHRTDP1ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |