Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MB | P02144 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765742 | 0.82 | LMNA (0.61) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL28485570 | 0.82 | LMNA (0.56) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL4472795 | 0.80 | LMNA (0.54) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL3071609 | 0.80 | LMNA (0.71) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL28486233 | 0.78 | LMNA (0.52) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL11800560 | 0.77 | LMNA (0.55) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL4961590 | 0.75 | LMNA (0.53) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL15798410 | 0.75 | LMNA (0.53) | LMNAALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL3791892 | 0.75 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5080845 | 0.75 | POLB (0.54) | LMNAALDH1A1GAATDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |