Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765742 | 0.78 | LMNA (0.61) | LMNAHSD17B10NAPRTALDH1A1GAA | |
| SCHEMBL8765733 | 0.78 | LMNA (0.56) | LMNAHSD17B10NAPRTKDM4EALDH1A1 | |
| SCHEMBL28485570 | 0.78 | LMNA (0.56) | LMNAHSD17B10NAPRTALDH1A1GAA | |
| SCHEMBL15798291 | 0.77 | MYC (0.49) | LMNAHSD17B10NAPRTKDM4EALDH1A1 | |
| SCHEMBL4960219 | 0.77 | LMNA (0.50) | LMNAHSD17B10NAPRTKDM4EALDH1A1 | |
| SCHEMBL4472795 | 0.77 | LMNA (0.54) | LMNAHSD17B10NAPRTKDM4EALDH1A1 | |
| SCHEMBL3071609 | 0.77 | LMNA (0.71) | LMNAHSD17B10NAPRTKDM4EALDH1A1 | |
| SCHEMBL844837 | 0.75 | ALDH1A1 (0.44) | HSD17B10KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL976774 | 0.75 | MPO (0.58) | HSD17B10NAPRTKDM4EALDH1A1TDP1 | |
| SCHEMBL618917 | 0.74 | L3MBTL1 (0.57) | LMNAHSD17B10NAPRTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995527-B | Preparation method of insensitive explosive TATB | 北京理工大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-111995527-A | Novel preparation method of insensitive explosive TATB | 北京理工大学 | 2020-11-27 | — | — | CN | disclosed |