Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5661525 | 0.82 | SIGMAR1 (0.53) | SIGMAR1SCN4A | |
| SCHEMBL5663771 | 0.82 | SIGMAR1 (0.53) | SIGMAR1SCN4A | |
| SCHEMBL5662052 | 0.81 | TSHR (0.40) | SIGMAR1MAPT | |
| SCHEMBL8765752 | 0.81 | SLC6A2 (0.51) | ARLMNAPTGS1 | |
| SCHEMBL9721664 | 0.81 | TSHR (0.40) | SIGMAR1MAPT | |
| SCHEMBL5664562 | 0.81 | TSHR (0.40) | SIGMAR1MAPT | |
| SCHEMBL4400577 | 0.79 | MAPT (0.47) | LMNAPOLBMAPTNPSR1 | |
| SCHEMBL3030980 | 0.78 | AR (0.35) | ARLMNAPOLBMAPTNPSR1 | |
| SCHEMBL1714720 | 0.78 | ALDH1A1 (0.51) | MAPTHRH3 | |
| SCHEMBL5259492 | 0.77 | MAOA (0.38) | FFAR1SIGMAR1ARLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |