Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615351 | 0.89 | RAPGEF4 (0.38) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL8765461 | 0.82 | ACHE (0.38) | RAPGEF4ACHEALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL13053162 | 0.82 | RAPGEF4 (0.45) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL8764966 | 0.79 | ALDH1A1 (0.42) | RAPGEF4ACHEALDH1A1TSHR | |
| SCHEMBL23607083 | 0.79 | ALDH1A1 (0.46) | RAPGEF4ACHEALDH1A1MAPTCYP1A2 | |
| SCHEMBL12313689 | 0.77 | ALDH1A1 (0.44) | RAPGEF4ACHEALDH1A1LMNAMAPT | |
| SCHEMBL12313736 | 0.77 | ALDH1A1 (0.44) | RAPGEF4ACHEALDH1A1LMNAMAPT | |
| SCHEMBL22550359 | 0.77 | CYP1A2 (0.41) | ACHEALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL12313674 | 0.77 | ALDH1A1 (0.44) | RAPGEF4ACHEALDH1A1LMNAMAPT | |
| SCHEMBL17138224 | 0.76 | PSMB5 (0.39) | ALDH1A1LMNACYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420207-B1 | Electrophotosensitive material and method of manufacturing the same | MITA INDUSTRIAL CO LTD (JP) | 1997-08-13 | — | — | EP | disclosed |
| EP-0390196-B1 | Electrophotosensitive material | MITA INDUSTRIAL CO LTD (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-5185228-A | Binder resin, charge transfer material; stability | MITA INDUSTRIAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-5128229-A | Polycarbonate, m-phenylenediamine derivative | MITA INDUSTRIAL CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5059503-A | Used for copying machine | MITA INDUSTRIAL CO., LTD. (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0420207-A2 | Electrophotosensitive material and method of manufacturing the same | MITA INDUSTRIAL CO. LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0390196-A2 | Electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |