Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.42 |
| ▸ | RARG | P13631 | 9/20 | 0.42 |
| ▸ | RARA | P10276 | 7/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | MDH1 | P40925 | 1/20 | 0.34 |
| ▸ | MDH2 | P40926 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079123 | 1.00 | RARB (0.42) | RARBRARGRARAHIF1AEPHX2 | |
| SCHEMBL8765826 | 0.92 | RARG (0.48) | RARBRARGRARAALDH1A1LMNA | |
| SCHEMBL8765802 | 0.92 | RARG (0.48) | RARBRARGRARAALDH1A1LMNA | |
| SCHEMBL9077434 | 0.80 | KDM4E (0.34) | RARBRARGRARAHIF1AEPHX2 | |
| SCHEMBL7687187 | 0.80 | NPC1 (0.36) | EPHX2 | |
| Hydrochloric Acid SCHEMBL9130755 | 0.80 | RARA (0.33) | RARBRARGRARAHIF1AEPHX2 | |
| SCHEMBL9158243 | 0.78 | MEN1 (0.36) | RARBRARGRARAHIF1AEPHX2 | |
| SCHEMBL3798383 | 0.75 | RARB (0.41) | RARBRARGRARAHIF1AEPHX2 | |
| SCHEMBL8766160 | 0.75 | RARA (0.46) | RARBRARGRARAEPHX2LMNA | |
| SCHEMBL8766140 | 0.75 | RARA (0.46) | RARBRARGRARAEPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547983-A | Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1996-08-20 | — | — | US | disclosed |