Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 5/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766162 | 0.82 | HMGCR (0.42) | CNR1NPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL8766950 | 0.82 | NPC1 (0.43) | ESRRGESRRBCNR1NPC1GAA | |
| SCHEMBL8766578 | 0.79 | HMGCR (0.44) | ESRRGESRRBGAAMAPTSMN1; SMN2 | |
| SCHEMBL3103368 | 0.74 | ESRRG (0.36) | ESRRGESRRBGAAMAPTPOLB | |
| SCHEMBL282093 | 0.71 | PPARD (0.47) | CYP2C19POLBKDM4EALDH1A1ESR1 | |
| SCHEMBL10912425 | 0.71 | TAAR1 (0.44) | NPC1GAACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8766544 | 0.70 | FDPS (0.37) | GAAMAPTSMN1; SMN2POLBKDM4E | |
| SCHEMBL8766494 | 0.70 | HMGCR (0.44) | GAASMN1; SMN2ALDH1A1FDPS | |
| SCHEMBL8766180 | 0.70 | GABRA1 (0.39) | GAAMAPTSMN1; SMN2POLBFDPS | |
| SCHEMBL8766481 | 0.69 | FDPS (0.36) | ESRRGGAACYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0559079-A1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1993-09-08 | — | — | EP | claimed |