Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091544 | 0.88 | NR1I2 (0.42) | MAPTALDH1A1POLBMEN1TP53 | |
| SCHEMBL2985103 | 0.79 | CA2 (0.37) | ESRRGMAPTALDH1A1GAALMNA | |
| SCHEMBL8483627 | 0.76 | ESRRG (0.48) | ESRRGMAPTALDH1A1GAALMNA | |
| SCHEMBL13645018 | 0.76 | CA2 (0.46) | ESRRGMAPTALDH1A1GAALMNA | |
| SCHEMBL8766151 | 0.74 | ESRRG (0.41) | ESRRGMAPTALDH1A1GAAPOLB | |
| SCHEMBL28538693 | 0.72 | CA2 (0.43) | ESRRGMAPTALDH1A1GAALMNA | |
| SCHEMBL8766591 | 0.72 | HMGCR (0.48) | ESRRGMAPTALDH1A1GAALMNA | |
| SCHEMBL13052619 | 0.72 | ESRRG (0.37) | ESRRGMAPTALDH1A1GAALMNA | |
| SCHEMBL2983378 | 0.71 | KMT2A (0.42) | ESRRGMAPTALDH1A1GAALMNA | |
| SCHEMBL13603850 | 0.71 | ALDH1A1 (0.40) | ESRRGMAPTALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |