Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875183 | 0.81 | PNMT (0.68) | PNMTHSP90AA1ALDH1A1NPC1RAB9A | |
| SCHEMBL27399387 | 0.78 | TSHR (0.42) | TSHRALDH1A1ATMNPSR1NPC1 | |
| SCHEMBL5515193 | 0.78 | ALDH1A1 (0.55) | TSHRALDH1A1ATMNPSR1NPC1 | |
| SCHEMBL3047696 | 0.77 | PGR (0.48) | PNMTHSP90AA1TSHRALDH1A1ATM | |
| SCHEMBL28812760 | 0.73 | PNMT (0.61) | PNMTHSP90AA1ALDH1A1NPC1RAB9A | |
| SCHEMBL8993336 | 0.72 | POLB (0.38) | HSP90AA1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL26420412 | 0.72 | ALDH1A1 (0.50) | PNMTHSP90AA1TSHRALDH1A1ATM | |
| SCHEMBL26778600 | 0.71 | TSHR (0.43) | PNMTHSP90AA1TSHRALDH1A1ATM | |
| SCHEMBL11620189 | 0.70 | AKR1B1 (0.39) | TSHRALDH1A1ATMNPSR1NPC1 | |
| SCHEMBL29809412 | 0.70 | SRD5A1 (0.47) | HSP90AA1TSHRALDH1A1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120074336-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) | 2012-03-29 | — | — | US | disclosed |
| US-20110077394-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | NATIONAL SCIENCE FOUNDATION | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077394-A1 | LIGHT-DRIVEN ROTARY MOLECULAR MOTORS | CCNA2, CCNO, SCO2 | PNMT 3281/4885HSP90AA1 4079/4885TSHR 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.