Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766012 | 0.85 | DRD2 (0.46) | GRIN2BACHEBACE1FYNDRD2 | |
| SCHEMBL8765757 | 0.80 | GRIN2B (0.63) | GRIN2BBCHEACHEBACE1 | |
| SCHEMBL8188704 | 0.73 | GRIN2B (0.64) | GRIN2BBCHEACHE | |
| SCHEMBL9315555 | 0.73 | MAOA (0.44) | GRIN2B | |
| Hydrochloric Acid SCHEMBL8178175 | 0.72 | GRIN2B (0.63) | GRIN2BBCHEACHE | |
| Hydrochloric Acid SCHEMBL8188653 | 0.72 | GRIN2B (0.63) | GRIN2BBCHEACHE | |
| SCHEMBL9776887 | 0.72 | GRIN2B (0.84) | GRIN2BBCHEACHEBACE1FYN | |
| Hydrochloric Acid SCHEMBL8186083 | 0.71 | GRIN2B (0.82) | GRIN2BBCHEACHEBACE1FYN | |
| SCHEMBL8309955 | 0.70 | GRIN2B (0.64) | GRIN2BBCHEACHEBACE1FYN | |
| Hydrochloric Acid SCHEMBL8310357 | 0.69 | GRIN2B (0.63) | GRIN2BBCHEACHEBACE1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |