Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD4 | P21917 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD5 | P21918 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766331 | 0.85 | GRIN2B (0.59) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL8765757 | 0.80 | GRIN2B (0.63) | GRIN2BACHEBACE1 | |
| SCHEMBL9306071 | 0.72 | GRIN2B (0.71) | DRD2DRD4DRD3GRIN2BFYN | |
| SCHEMBL6133948 | 0.72 | GRIN2B (0.71) | DRD2DRD4DRD3GRIN2BFYN | |
| SCHEMBL9304253 | 0.72 | GRIN2B (0.71) | DRD2DRD4DRD3GRIN2BFYN | |
| Bromide SCHEMBL9304413 | 0.71 | GRIN2B (0.69) | DRD2DRD4DRD3GRIN2BFYN | |
| Bromide SCHEMBL9304418 | 0.71 | GRIN2B (0.69) | DRD2DRD4DRD3GRIN2BFYN | |
| Bromide SCHEMBL9303647 | 0.71 | GRIN2B (0.69) | DRD2DRD4DRD3GRIN2BFYN | |
| SCHEMBL9315555 | 0.68 | MAOA (0.44) | GRIN2B | |
| SCHEMBL5142005 | 0.68 | GRIN2B (0.59) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583485-B1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5387710-A | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |