SCHEMBL8766370

SCHEMBL8766370

Ic1ccc2c(c1)CC=C2

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNMT P11086 6/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
TDP2 O95551 1/20 0.32
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765334 0.82 CA1 (0.36) PNMTADRA2AADRA2BADRA2CCA1
SCHEMBL13523394 0.78 ADRA2A (0.37) PNMTADRA2AADRA2BADRA2CTDP2
SCHEMBL34474640 0.73 CA1 (0.33) CA1CA2PDE3A
SCHEMBL1896564 0.73 HTR2C (0.38) PNMTADRA2AADRA2BADRA2C
SCHEMBL31513999 0.73 CYP1A2 (0.35) ADRA2A
SCHEMBL31513977 0.73 HTR2C (0.38) PNMTADRA2AADRA2BADRA2C
SCHEMBL4856868 0.73 CYP1A2 (0.35) ADRA2A
SCHEMBL8031077 0.73 CA1 (0.33) CA1CA2PDE3A
SCHEMBL1478133 0.73 PNMT (0.35) PNMTADRA2AADRA2BADRA2CTDP2
SCHEMBL9442055 0.72 CA1 (0.31) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058812-A Double-active-center metallocene complex and preparation method and application thereof 万华化学集团股份有限公司 2025-05-30 CN disclosed
EP-3907225-A1 IMIDAZOPYRIDINE DERIVATIVE COMPOUNDS AND USE OF SAME Hanmi Pharm. Co., Ltd. (KR) 2021-11-10 EP disclosed
US-10954178-B1 Synthesis of haloindenes THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-03-23 US disclosed
US-10954178-B1 Synthesis of haloindenes THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-03-23 US disclosed
CN-112105654-A Curable resin mixture, curable resin composition, and cured product thereof 日本化药株式会社 2020-12-18 CN disclosed
WO-2020031935-A1 CURABLE RESIN MIXTURE, CURABLE RESIN COMPOSITION, AND CURED PRODUCT 日本化薬株式会社 2020-02-13 WO disclosed
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed